Traditional recruitment of patients with diabetes or prediabetes has included broad, imprecise methods, such as mass mailings, advertisements, community events, and clinician referrals. The D2d met its enrollment target in a transformative way by utilizing Electronic Health Records (EHR)...
The last participant study visit was completed at the Northwestern site. This is a very exciting time for both participants and researchers alike! Since the first participant visit in the fall of 2013, more than 29,401 study visits occurred...
Randomized clinical trials that have public health implications but no or low potential for commercial gain are predominantly funded by governmental (e.g., National Institutes of Health (NIH)) and not-for-profit organizations. Judicious management of research studies’ budgets in a milieu...
A future long-term observational follow-up study (with no pills or visits) is being considered for the purpose of collecting simple health information to learn more about vitamin D and health (e.g., diabetes, cancer, heart disease). In anticipation of this...
D2d is the largest clinical trial designed specifically to examine the causal relationship between vitamin D supplementation and the development of diabetes. D2d is also the largest U.S.-based study to have assembled and followed a contemporary cohort of people...
The annual meeting of the D2d research team is held in Washington D.C.. On Sunday evening, Principal Investigator Dr. Pittas presents the State of D2d, which remains very strong, especially following the ‘green light’ by the DSMB following its review...
The Data and Safety Monitoring Board (DSMB) reviews the results of the interim analysis. This is a critical juncture in the conduct of any clinical trial as the DSMB may recommend that the trial be stopped for futility, safety...
The National Diabetes Education Program created the Small Steps. Big Rewards. GAME PLAN. toolkit to deliver basic type 2 diabetes prevention information to individuals at risk. Among D2d participants who are at risk for diabetes, the GAME PLAN improved knowledge...
A patient from the New York Lenox Hospital site is the 2,423rd and last participant enrolled in D2d. The participant completed the study. Congratulations to the amazing research staff at all sites for recruiting a wonderful group of dedicated...
A participant from the Atlanta VA Medical Center site is the 2,382nd participant enrolled in D2d. The study’s recruitment goal is achieved. This is a major accomplishment as most trials never reach their recruitment goal. The participant completed the...