Publications

Publications

Publications

Racial differences in measures of glycemia in the Vitamin D and Type 2 Diabetes (D2d) Study: a secondary analysis of a randomized trial.

LeBlanc ES, Pittas AG, Nelson J, Chatterjee R, Rasouli N, Rhee M, Pratley RE, Desouza CV, Neff LM, Peters AM, Dagogo-Jack S, Hsia DS, D2d Research Group. Racial differences in measures of glycemia in the Vitamin D and Type 2 Diabetes (D2d) Study: a secondary analysis of a randomized trial. BMJ Open Diab Res Care 2024;12:e003613. doi:10.1136/bmjdrc-2023-003613

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Effect of vitamin D on regression to normal glucose regulation and individual glycemic measures: A secondary analysis among participants adherent to the trial protocol in the randomized clinical trial vitamin D and type 2 diabetes (D2d) study.

Hsia DS, Nelson J, Vickery EM, Rasouli N, LeBlanc ES, Kim S, Brodsky I, Pratley R, Dawson-Hughes B, Pittas AG; D2d Research Group. Effect of vitamin D on regression to normal glucose regulation and individual glycemic measures: A secondary analysis among participants adherent to the trial protocol in the randomized clinical trial vitamin D and type 2 diabetes (D2d) study. Diabetes Res Clin Pract. 2023 Aug;202:110792. doi: 10.1016/j.diabres.2023.110792. PMID: 37343726; PMCID: PMC10491428.

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Glycemic and metabolic sub-classification of prediabetes and risk factors for cardiovascular disease in the D2d cohort.

Kashyap SR, Desouza C, Aroda VR, Kim SH, Neff LM, Wu SS, Raskin P, Pratley R; D2d Research Group. Glycemic and metabolic sub-classification of prediabetes and risk factors for cardiovascular disease in the D2d cohort. Am J Prev Cardiol. 2023 Jul 27;15:100525. doi: 10.1016/j.ajpc.2023.100525. PMID: 37650052; PMCID: PMC10462804.

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Effect of intratrial mean 25(OH)D concentration on diabetes risk, by race and weight: an ancillary analysis in the D2d study.

Chatterjee R, Davenport CA, Vickery EM, Johnson KC, Kashyap SR, LeBlanc ES, Nelson J, Dagogo-Jack S, Pittas AG, Hughes BD; D2d Research Group. Effect of intratrial mean 25(OH)D concentration on diabetes risk, by race and weight: an ancillary analysis in the D2d study. Am J Clin Nutr. 2023 Jul;118(1):59-67. doi: 10.1016/j.ajcnut.2023.03.021. Epub 2023 Mar 29. PMID: 37001590; PMCID: PMC10447481.

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Indices of hepatic steatosis and fibrosis in prediabetes and association with diabetes development in the vitamin D and type 2 diabetes study.

Corbin KD, Pittas AG, Desouza C, Grdinovac KK, Herzig KH, Kashyap SR, Kim SH, Nelson J, Rasouli N, Vickery EM, Knowler WC, Pratley RE. Indices of hepatic steatosis and fibrosis in prediabetes and association with diabetes development in the vitamin D and type 2 diabetes study. J Diabetes Complications. 2023 Jun;37(6):108475. doi: 10.1016/j.jdiacomp.2023.108475. Epub 2023 Apr 12. PMID: 37104979; PMCID: PMC10683797.

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Effect of vitamin D supplementation on circulating fibroblast growth factor-23 concentration in adults with prediabetes.

Ceglia L, Pittas AG, Dawson-Hughes B. Effect of vitamin D supplementation on circulating fibroblast growth factor-23 concentration in adults with prediabetes. Aging Clin Exp Res. 2023 Mar;35(3):525-530. doi: 10.1007/s40520-022-02338-y. Epub 2023 Jan 11. PMID: 36631721.

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Vitamin D and Risk for Type 2 Diabetes in People With Prediabetes A Systematic Review and Meta-analysis of Individual Participant Data From 3 Randomized Clinical Trials.

Anastassios G. Pittas, Tetsuya Kawahara, Rolf Jorde, Bess Dawson-Hughes, Ellen M. Vickery, Edith Angellotti, Jason Nelson, Thomas A. Trikalinos, and Ethan M. Balk Vitamin D and Risk for Type 2 Diabetes in People With Prediabetes A Systematic Review and Meta-analysis of Individual Participant Data From 3 Randomized Clinical Trials. Ann Intern Med. 2023;176:355-363. doi:10.7326/M22-3018

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Response to Comment on Hands et al. Vitamin D and Risk for Type 2 Diabetes in People With Prediabetes.

Anastassios G. Pittas, Tetsuya Kawahara, Rolf Jorde, Bess Dawson-Hughes and Ethan M. Balk. Response to Comment on Hands et al. Vitamin D and Risk for Type 2 Diabetes in People With Prediabetes. Ann Intern Med 2023. August. https://doi.org/10.7326/L23-0202

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The effect of vitamin D supplementation on cardiovascular risk in patients with prediabetes: A secondary analysis of the D2d study.

Desouza C, Chatterjee R, Vickery EM, Nelson J, Johnson KC, Kashyap SR, Lewis MR, Margolis K, Pratley R, Rasouli N, Sheehan PR, Pittas AG; D2d Research Group. The effect of vitamin D supplementation on cardiovascular risk in patients with prediabetes: A secondary analysis of the D2d study. J Diabetes Complications. 2022 Aug;36(8):108230. doi: 10.1016/j.jdiacomp.2022.108230. Epub 2022 Jun 12. PMID: 35753926.

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Safety and tolerability of high-dose daily vitamin D3 supplementation in the vitamin D and type 2 diabetes (D2d) study-a randomized trial in persons with prediabetes.

Johnson KC, Pittas AG, Margolis KL, Peters AL, Phillips LS, Vickery EM, Nelson J, Sheehan PR, Reboussin D, Malozowski S, Chatterjee R; D2d research group. Safety and tolerability of high-dose daily vitamin D3 supplementation in the vitamin D and type 2 diabetes (D2d) study-a randomized trial in persons with prediabetes. Eur J Clin Nutr. 2022 Aug;76(8):1117-1124. doi: 10.1038/s41430-022-01068-8. PMID: 35140313

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Effects of vitamin D supplementation on insulin sensitivity and secretion in prediabetes

Rasouli N, Brodsky IG, Chatterjee R, Kim SH, Pratley RE, Staten MA, Pittas AG; D2d Research Group. Effects of Vitamin D Supplementation on Insulin Sensitivity and Secretion in Prediabetes. J Clin Endocrinol Metab. 2022;107(1):230-240. doi: 10.1210/clinem/dgab649. PMID: 34473295

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Effect of Vitamin D Supplementation on Kidney Function in Adults with Prediabetes: A Secondary Analysis of a Randomized Trial

Sun H. Kim, Irwin G. Brodsky, Ranee Chatterjee, Sangeeta R. Kashyap, William C. Knowler, Emilia Liao, Jason Nelson, Richard Pratley, Neda Rasouli, Ellen M. Vickery, Mark Sarnak, Anastassios G. Pittas, D2d Research Group. Effect of Vitamin D Supplementation on Kidney Function in Adults with Prediabetes: A Secondary Analysis of a Randomized Trial. Clinical Journal of the American Society of Nephrology. 2021;16(8):1201-9. doi: 10.2215/CJN.00420121.

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Vitamin D Supplementation for Prevention of Cancer: The D2d Cancer Outcomes (D2dCA) Ancillary Study

Ranee Chatterjee, Paul Fuss, Ellen M. Vickery, Erin S. LeBlanc, Patricia R. Sheehan, Michael R. Lewis, Rowena J. Dolor, Karen C. Johnson, Sangeeta R. Kashyap, Jason Nelson, Anastassios G. Pittas, and the D2d Research Group. Vitamin D Supplementation for Prevention of Cancer: The D2d Cancer Outcomes (D2dCA) Ancillary Study. Journal of Clinical Endocrinology and Metabolism. 2021;106(9):2676-9. doi:10.1210/clinem/dgab153.

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Vitamin D Supplementation for Prevention of Type 2 Diabetes Mellitus: To D or Not to D?

Anastassios G. Pittas, Rolf Jorde, Tetsuya Kawahara, and Bess Dawson-Hughes. Vitamin D Supplementation for Prevention of Type 2 Diabetes Mellitus: To D or Not to D? The Journal of Clinical Endocrinology & Metabolism. Volume 105, Issue 12, October 2020. doi:10.1210/clinem/dgaa594.

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Intratrial Exposure to Vitamin D and New-Onset Diabetes Among Adults With Prediabetes: A Secondary Analysis From the Vitamin D and Type 2 Diabetes (D2d) Study

Bess Dawson-Hughes, Myrlene A. Staten, William C. Knowler, Jason Nelson, Ellen M. Vickery, Erin S. LeBlanc, Lisa M. Neff, Jean Park, Anastassios G. Pittas, D2d Research Group. Intratrial Exposure to Vitamin D and New-Onset Diabetes Among Adults With Prediabetes: A Secondary Analysis From the Vitamin D and Type 2 Diabetes (D2d) Study. Diabetes Care. 2020;43(12):2916-22. doi: 10.2337/dc20-1765.

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Untangling the Gordian Knot of Vitamin D Supplementation and Type 2 Diabetes Prevention

Anastassios G. Pittas, Ethan M. Balk. Untangling the Gordian Knot of Vitamin D Supplementation and Type 2 Diabetes Prevention. Diabetes Care 2020;43:1375–1377. doi: 10.2337/dci20-0011.

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Reproducibility of a prediabetes classification in a contemporary population

Chhavi Chadha, Anastassios G. Pittas, Christine W. Lary, William C. Knowler, Ranee Chatterjee, Lawrence S. Phillips, Vanita R. Aroda, Michael R. Lewis, Richard Pratley, Myrlene A. Staten, Jason Nelson, Neda Rasouli, Irwin Brodsky, D2d Research Group. Reproducibility of a prediabetes classification in a contemporary population. Metabolism Open. 2020;6:100031. doi: 10.1016/j.metop.2020.100031.

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Implications of the Hemoglobin Glycation Index on the Diagnosis of Prediabetes and Diabetes

Hsia DS, Rasouli N, Pittas AG, Lary CW, Peters A, Lewis MR, Kashyap SR, Johnson KC, LeBlanc ES, Phillips LS, Hempe JM, Desouza CV; D2d Research Group. Implications of the Hemoglobin Glycation Index on the Diagnosis of Prediabetes and Diabetes. J Clin Endocrinol Metab. 2020;105(3):e118-e126. doi: 10.1210/clinem/dgaa029. PMID: 31965161

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Vitamin D Supplementation and Prevention of Type 2 Diabetes

Anastassios G Pittas, Bess Dawson-Hughes, Patricia Sheehan, James H Ware, William C Knowler, Vanita R Aroda, Irwin Brodsky, Lisa Ceglia, Chhavi Chadha, Ranee Chatterjee, Cyrus Desouza, Rowena Dolor, John Foreyt, Paul Fuss, Adline Ghazi, Daniel S Hsia, Karen C Johnson, Sangeeta R Kashyap, Sun Kim, Erin S LeBlanc, Michael R Lewis, Emilia Liao, Lisa M Neff, Jason Nelson, Patrick O’Neil, Jean Park, Anne Peters, Lawrence S Phillips, Richard Pratley, Philip Raskin, Neda Rasouli, David Robbins, Clifford Rosen, Ellen M Vickery, Myrlene Staten, D2d Research Group. Vitamin D Supplementation and Prevention of Type 2 Diabetes. New England Journal of Medicine. 2019;381(6):520-30. doi: 10.1056/NEJMoa1900906.

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Response to Comments. Vitamin D Supplementation and Prevention of Type 2 Diabetes.

Pittas AG, Dawson-Hughes B and Staten M. Response to comments. Vitamin D Supplementation and Prevention of Type 2 Diabetes N Engl J Med 2019; 381:1784-1786. DOI: 10.1056/NEJMc1912185

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Establishing an electronic health record-supported approach for outreach to and recruitment of persons at high risk of type 2 diabetes in clinical trials: The vitamin D and type 2 diabetes (D2d) study experience.

Vanita R Aroda, Patricia R Sheehan, Ellen M Vickery, Myrlene A Staten, Erin S LeBlanc, Lawrence S Phillips, Irwin G Brodsky, Chhavi Chadha, Ranee Chatterjee, Miranda G Ouellette, Cyrus Desouza, Anastassios G Pittas, D2d Research Group. Establishing an electronic health record-supported approach for outreach to and recruitment of persons at high risk of type 2 diabetes in clinical trials: The vitamin D and type 2 diabetes (D2d) study experience. Clinical Trials. 2019;16(3):306-15. doi: 10.1177/1740774519839062.

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Baseline Characteristics of the Vitamin D and Type 2 Diabetes (D2d) Study: A Contemporary Prediabetes Cohort That Will Inform Diabetes Prevention Efforts

Erin S LeBlanc, Richard E Pratley, Bess Dawson-Hughes, Myrlene A Staten, Patricia R Sheehan, Michael R Lewis, Anne Peters, Sun H Kim, Ranee Chatterjee, Vanita R Aroda, Chhavi Chadha, Lisa M Neff, Irwin G Brodsky, Clifford Rosen, Cyrus V Desouza, John P Foreyt, Daniel S Hsia, Karen C Johnson, Philip Raskin, Sangeeta R Kashyap, Patrick O’Neil, Lawrence S Phillips, Neda Rasouli, Emilia P Liao, David C Robbins, Anastassios G Pittas, D2d Research Group. Baseline characteristics of the Vitamin D and Type 2 Diabetes (D2d) Study: a contemporary prediabetes cohort that will inform diabetes prevention efforts. Diabetes Care. 2018;41(8):1590-9. doi: 10.2337/dc18-0240.

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Financial management of large, multi-center trials in a challenging funding milieu

Olivia Lovegreen, Danielle Riggs, Myrlene A Staten, Patricia Sheehan, Anastassios G Pittas. Financial management of large, multi-center trials in a challenging funding milieu. Trials. 2018;19:267. doi: 10.1186/s13063-018-2638-z.

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Assessment of a National Diabetes Education Program diabetes prevention toolkit: The D2d experience

Roshni Devchand, Patricia Sheehan, Joanne M. Gallivan, Diane M. Tuncer, Christina Nicols, D2d Research Group. Assessment of a National Diabetes Education Program diabetes prevention toolkit: The D2d experience. Journal of the American Association of Nurse Practitioners. 2017;29(9):514-20. doi: 10.1002/2327-6924.12499.

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Management of Hemoglobin Variants Detected Incidentally in HbA1c Testing: A Common Problem Currently Lacking a Standard Approach

Michael R. Lewis, Robert C. Macauley, Patricia R. Sheehan, Myrlene A. Staten, Lawrence S. Phillips, Neda Rasouli, Anastassios G. Pittas, D2d Research Group.  Management of hemoglobin variants detected incidentally in HbA1c testing: a common problem currently lacking a standard approach. Diabetes Care. 2017;40(2);e8-9. doi: 10.2337/dc16-1667.

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Response to Comment on Lewis et al. Management of Hemoglobin Variants Detected Incidentally in HbA1c Testing: A Common Problem Currently Lacking a Standard Approach. Diabetes Care 2017;40:e8–e9

Michael R. Lewis, Patricia R. Sheehan, Myrlene A. Staten, Lawrence S. Phillips, Anastassios G. Pittas. Response to Comment on Lewis et al. Management of Hemoglobin Variants Detected Incidentally in HbA1c Testing: A Common Problem Currently Lacking a Standard Approach. Diabetes Care 2017 Oct; 40(10): e150-e151. doi: 10.2337/dci17-0020.

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Rationale and Design of the Vitamin D and Type 2 Diabetes (D2d) Study: A Diabetes Prevention Trial

Anastassios G. Pittas, Bess Dawson-Hughes, Patricia R. Sheehan, Clifford J. Rosen, James H. Ware, William C. Knowler, Myrlene A. Staten, D2d Research Group. Rationale and Design of the Vitamin D and Type 2 Diabetes Study: A Diabetes Prevention Trial. Diabetes Care. 2014;37(12):3227-34. doi: 10.2337/dc14-1005.

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