CaDDM clinical trial results are published

Results of the Vitamin D and Calcium Homeostasis for Prevention of Type 2 Diabetes (CaDDM) study support a mechanistic link between vitamin D and diabetes risk among adults at risk for diabetes or with early diabetes not requiring medications. In...

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U34 planning grant is awarded

Dr. Pittas and colleagues are awarded a Multi-Center Clinical Study Implementation Planning Cooperating Agreement (U34) grant. The NIDDK-supported grant provides support to a core team of investigators to finalize the study design, develop the necessary infrastructure and prepare for...

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U34 planning grant application undergoes scientific review

The U34 grant application undergoes a highly favorable scientific peer review by a NIH Special Emphasis Study Section, specifically convened to review the application. Over the next year, NIDDK continues to deliberate the merits of the D2d study and...

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Association between higher blood level of vitamin D and lower risk of diabetes among women is reported

An observational study in the Nurses’ Health Study – a longitudinal cohort of women – supports an association between higher blood level of vitamin D and lower risk of developing diabetes. After adjusting for many factors known to influence diabetes...

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U34 planning grant application is submitted

Dr. Pittas and colleagues submit the Multi-Center Clinical Study Implementation Planning Cooperating Agreement (U34) grant application to NIH.  The goals of the U34 grant are to: (1) Permit early peer review of the rationale for the proposed clinical study;...

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NIDDK allows submission of a U34 planning grant application to plan the D2d study

During the spring and early summer of 2010, the D2d concept goes through additional rounds of review within NIDDK. In July of 2010, Dr. Pittas receives the positive news that NIDDK has approved submission of a Multi-Center Clinical Study...

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NIDDK Large Studies Committee reviews preliminary concept of D2d

In December of 2009, Dr. Pittas submits a pre-application to NIDDK proposing the study concept of D2d. The scientific justification of D2d and the preliminary study design go through multiple rigorous reviews by scientific committees within NIDDK, starting in...

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Observational study to examine the association between vitamin D status and future diabetes risk in adults with prediabetes is funded

Dr. Pittas and colleagues receive funding by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and the Office of Dietary Supplements (ODS) of the National Institutes of Health (NIH) to assess the longitudinal association between vitamin D status...

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Observational study to examine the association between vitamin D status and future diabetes risk in women is funded

Dr. Pittas and colleagues receive funding by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH) to assess the longitudinal association between vitamin D status – assessed by blood level of 25-hydroxyvitamin...

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Effect of combined Calcium and Vitamin D supplementation in non-diabetic adults is published

In a post-hoc analysis using data from a completed trial, vitamin D and calcium supplementation given over 3 years improved insulin resistance and fasting blood glucose in non-diabetic adults aged 65 who had impaired fasting glucose (IFG) at baseline (see...

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