Story
2017
![](https://d2dstudy.org/wp-content/uploads/2017/02/D2d_News_17_1022.jpg)
OCTOBER 22, 2017
Fifth Investigators’ Meeting
The annual meeting of the D2d research team is held in Washington D.C. to discuss study progress and plan for the future of D2d.
![](https://d2dstudy.org/wp-content/uploads/2017/02/D2d_News_17_0925-1.jpg)
SEPTEMBER 25, 2017
Interim analysis results are reviewed
The Data and Safety Monitoring Board (DSMB) reviews the results of the interim analysis and recommends that the D2d study proceed to completion as planned.
![](https://d2dstudy.org/wp-content/uploads/2017/02/D2d_News_02.jpg)
AUGUST 3, 2017
D2d Publication
Assessment of a National Diabetes Education Program diabetes prevention toolkit: The D2d experience. Click here to read the article.
![](https://d2dstudy.org/wp-content/uploads/2017/02/D2d_News_17_0202.jpg)
FEBRUARY 08, 2017
D2d enrolls last participant
The 2,423rd and last participant enrolls in D2d. Congratulations to the amazing staff for recruiting a wonderful group of dedicated participants.
2016
![](https://d2dstudy.org/wp-content/uploads/2017/02/D2d_News_16_1213B.jpg)
DECEMBER 16, 2016
D2d enrolls 2,382nd participant
A participant from the Atlanta VA Medical Center site is the 2,382nd participant enrolled in D2d. The study’s recruitment goal is achieved.
![](https://d2dstudy.org/wp-content/uploads/2017/02/D2d_News_16_1129.jpg)
NOVEMBER 29, 2016
D2d Publication
Management of Hemoglobin Variants Detected Incidentally in HbA1c Testing: A Common Problem Currently Lacking a Standard Approach. Click here to read the article.
![](https://d2dstudy.org/wp-content/uploads/2017/02/D2d_News_17_0925.jpg)
SEPTEMBER 25, 2016
D2d Investigators’ Meeting
The annual meeting of the D2d research team is held in Arlington, VA.
![](https://d2dstudy.org/wp-content/uploads/2017/02/D2d_News_16_0627A.jpg)
JUNE 27, 2016
D2d enrolls 2,000th participant
A participant from the Pennington Biomedical Research Center site is the 2,000th participant enrolled in D2d.
2015
![1500 1500](https://d2dstudy.org/wp-content/uploads/2017/02/1500-350x160.jpg)
NOVEMBER 20, 2015
D2d enrolls 1,500th participant
A participant from the Northwestern University site is the 1,500th participant enrolled in D2d
![](https://d2dstudy.org/wp-content/uploads/2017/02/D2d_News_15_1108.jpg)
NOVEMBER 8, 2015
D2d Investigators’ Meeting
The annual meeting of the D2d research team is held in Arlington, VA. Click here to see photos from this year’s meeting.
![](https://d2dstudy.org/wp-content/uploads/2017/02/1000-comic-300x114.png)
APRIL 20, 2015
D2d enrolls 1,000th participant
A participant from the MedStar Community Clinical Research Center D2d site was the 1,000th participant enrolled in D2d
2014
![](https://d2dstudy.org/wp-content/uploads/2017/02/D2d_News_14_1117.jpg)
NOVEMBER 17, 2014
D2d Investigators’ Meeting
The annual meeting of the D2d research team is held in Crystal City, MD. Click here to see photos from the meeting
![September 2010 September 2010](https://d2dstudy.org/wp-content/uploads/2017/02/September-2010-e1516292703964-350x155.png)
SEPTEMBER, 2014
First D2d Publication
Rationale and Design of the Vitamin D and Type 2 Diabetes (D2d) Study: A Diabetes Prevention Trial is published. Click here to read the article.
![](https://d2dstudy.org/wp-content/uploads/2017/02/500-300x154.png)
AUGUST 28, 2014
D2d enrolls 500th participant
A participant from the Atlanta VA Medical Center site is the 500th participant enrolled in D2d.
2013
![1st participant 1st participant](https://d2dstudy.org/wp-content/uploads/2017/02/1st-participant-350x180.png)
NOVEMBER 1, 2013
D2d enrolls 1st participant
A participant from the University of Kansas site is the 1st participant enrolled in D2d.
![](https://d2dstudy.org/wp-content/uploads/2017/02/D2d_News_13_1015.jpg)
OCTOBER 15, 2013
Recruitment begins
D2d begins screening people at high risk for diabetes to join the study. Screening takes place in many study sites throughout the United States. The first participant to is screened at the Florida Hospital Translational Research Institute site. Click here to see where D2d takes place.
![](https://d2dstudy.org/wp-content/uploads/2017/02/D2d_News_13_0919.jpg)
SEPTEMBER 19, 2013
First NIDDK supported trial to use IRBShare
D2d is the first NIDDK-supported trial and the fifth NIH-supported study to join the IRB Share program.
![](https://d2dstudy.org/wp-content/uploads/2017/02/D2d_News_14_1117.jpg)
JULY 9-10, 2013
Investigators’ Kick-off meeting
The first meeting of the D2d research team is held in Bethesda, MD. D2d investigators and coordinators plan a successful study launch.
![](https://d2dstudy.org/wp-content/uploads/2017/02/D2d_News_13_0601.jpg)
JUNE 1, 2013
U01 grant to conduct D2d is awarded
Tufts Medical Center receives the U01 cooperative agreement grant to conduct D2d. The grant is supported by NIDDK and the NIH Office of Dietary Supplements.
![](https://d2dstudy.org/wp-content/uploads/2017/02/D2d_News_13_0709-10.jpg)
MAY 31, 2013
DSMB inaugural meeting
The inaugural meeting of the D2d Data Safety Monitoring Board (DSMB) takes place in Bethesda, MD. The DSMB reviews and approves the study’s protocol.
2012
![](https://d2dstudy.org/wp-content/uploads/2017/02/meeting.review-350x160.jpg)
SEPTEMBER 14, 2012
U01 cooperative agreement grant is reviewed
The U01 grant application undergoes a favorable scientific peer review by NIH Special Emphasis Study Section.
![binder binder](https://d2dstudy.org/wp-content/uploads/2017/02/binder-e1519317908368-350x160.png)
JUNE 5, 2012
U01 cooperative agreement grant is submitted
The D2d team submits a 1,140 page U01 grant application to NIH for funding to conduct D2d.
![D2d_News_12_0330 D2d_News_12_0330](https://d2dstudy.org/wp-content/uploads/2017/02/D2d_News_12_0330.jpg)
MARCH 30, 2012
Progress of U34 planning phase is reviewed favorably
The NIDDK External Evaluation Committee reviews the progress of the U34 planning phase and recommends that the D2d team proceeds with submitting a U01 grant application.
![DPP DPP](https://d2dstudy.org/wp-content/uploads/2017/02/DPP-350x300.png)
MARCH, 2012
Association between higher blood vitamin D level and lower risk of Diabetes in the Diabetes Prevention Program is reported
An observational study in the Diabetes Prevention Program, a cohort of people with prediabetes, supports an association between high blood levels of vitamin D and lower risk of developing diabetes. Click here to read the article.
2011
![](https://d2dstudy.org/wp-content/uploads/2017/02/NIDDK-logo-300x150.png)
JULY 20, 2011
U34 planning grant is awarded
Dr. Pittas and colleagues are awarded a NIH-supported planning grant which provides financial support to finalize the study design of D2d, develop the necessary infra-structure and prepare for the U01 grant application to seek support to conduct D2d.
2010
![NHS NHS](https://d2dstudy.org/wp-content/uploads/2017/02/NHS-400x350.png)
SEPTEMBER 2010
Association between blood level of vitamin D and Diabetes Risk in the Nurses’ Health Study is reported
An observational study in the Nurses’ Health Study, a longitudinal cohort of women, supports an association between low blood levels of vitamin D and development of diabetes. Click here to read the article.
![](https://d2dstudy.org/wp-content/uploads/2017/02/D2d_News_10_0730.jpg)
JULY 30, 2010
U34 planning grant application is submitted
Dr. Pittas and colleagues submit the U34 planning grant application to NIH. The grant will provide critical funding to complete the design of D2d, establish the D2d research team and create the required organizational structure to conduct the study.
![](https://d2dstudy.org/wp-content/uploads/2017/02/D2d_News_10_0701.jpg)
JULY 01, 2010
NIDDK allows submission of a grant application to plan the D2d study
Dr. Pittas and his team receive approval from NIDDK to submit a U34 planning grant application to NIH to plan D2d.
![](https://d2dstudy.org/wp-content/uploads/2017/02/D2d_News_03.jpg)
JANUARY 2010
NIDDK Large Studies Committee reviews preliminary concept of D2d
The scientific justification for D2d and the preliminary concept of the study design go through multiple rigorous internal reviews by NIDDK.
2006
2002
![](https://d2dstudy.org/wp-content/uploads/2017/02/D2d_News_05.jpg)
SEPTEMBER 30, 2006
CaDDM clinical trial is funded
The Vitamin D and Calcium Homeostasis for Prevention of Type 2 Diabetes (CaDDM) study is funded by the National Institutes of Health (NIDDK and the Office of Dietary Supplements). The CaDDM study enrolls its first patient in September of 2007.
![](https://d2dstudy.org/wp-content/uploads/2017/02/D2d_News_04.jpg)
JULY 2002
Idea is conceived
The idea that vitamin D is linked to risk of developing type 2 diabetes is conceived by Dr. Pittas.